The colonic epithelium has an interface between your micro-organisms and host colonising the gastrointestinal tract. isolates demonstrated that they were highly responsive to bacterial challenge, with up-regulation of mRNA for TLR1C4. In contrast, CACO-2 cells were refractive to bacterial challenge, showing little difference in mRNA levels. TLR3 was induced in HT29 only by Gram-positive commensals… Continue reading The colonic epithelium has an interface between your micro-organisms and host