Homeostasis of the endoplasmic reticulum (ER) is essential for normal cellular functions. reporter and ChIP assays we dissected the Ufm1 promoter and found that Ufm1 was a potential target of Xbp-1 one of NBP35 crucial transcription factors in UPR. We further examined the effect of Xbp-1 deficiency on the expression of the Ufm1 components. Interestingly… Continue reading Homeostasis of the endoplasmic reticulum (ER) is essential for normal cellular