In one of the earliest events in the initiation of antigen-driven antibody responses na?ve IgM- and IgD-expressing B cells enter germinal centers where they irreversibly isotype switch to the expression of predominately IgG B cell TAK-441 receptors (BCRs). essential for antibody memory responses including enhanced calcium responses in IgG BCR expressing B cells (Wakabayashi et… Continue reading In one of the earliest events in the initiation of antigen-driven