Outer membrane vesicles (OMVs) released by some Gram-negative bacterias have been shown to exert immunomodulatory effects that favor the establishment of the illness. Treatment of THP-1 cells with OMVs during IFN-γ activation reduced significantly the inducing effect of this cytokine on MHC-II manifestation. OMVs induced a dose-dependent increase of ICAM-1 manifestation on THP-1 cells and… Continue reading Outer membrane vesicles (OMVs) released by some Gram-negative bacterias have been