Hypoxia induces the expansion of glioblastoma stem cells (GSCs) however the

Hypoxia induces the expansion of glioblastoma stem cells (GSCs) however the system underlying it really is even now unclear. activated in GSC preferentially. Inhibition of the pathways partly decreases the hypoxia-induced activation from the Notch pathway and following GSC maintenance. Used together our results claim that HIF-1requires Notch pathway to operate a vehicle the maintenance… Continue reading Hypoxia induces the expansion of glioblastoma stem cells (GSCs) however the