Background Beta-2 adrenergic receptor (β2AR) agonists are critical treatments for asthma. Blot and immunofluorescence. HAECs and airway tissue from controls and asthmatics were evaluated for I5LO1 PEBP1 and GRK2. Results Pretreatment with ISO or IL-13 decreased ISO-induced cAMP generation compared to ISO for 10 min alone paralleled by increases in β2AR and GRK2 phosphorylation. GRK2… Continue reading Background Beta-2 adrenergic receptor (β2AR) agonists are critical treatments for asthma.