RAS proteins are small GTPases that regulate signalling networks that control cellular survival and proliferation. [23,24]. Although this might suggest that isoform-specific differences may be hard to discern in this noisy background, work demonstrates that functional differences exist between RAS isoforms. Genetically engineered mice inducibly expressing KRASG12D and NRASG12D from their endogenous loci exhibited clear… Continue reading RAS proteins are small GTPases that regulate signalling networks that control