Ataxia telangiectasia mutated (ATM) kinase has a crucial function as a

Ataxia telangiectasia mutated (ATM) kinase has a crucial function as a professional control in the cellular DNA harm response. squalene elevated Wip1 reflection in cells and covered up ATM account activation in IR-treated cells. Consistent with the potential inhibition of ATM by squalene, IR-induced phosphorylation of ATM effectors such as g53 (Ser15) and Chk1 (Ser317)… Continue reading Ataxia telangiectasia mutated (ATM) kinase has a crucial function as a