Blood-brain barrier (BBB) disruption and consequent edema formation contributes to the development of early brain injury following subarachnoid hemorrhage (SAH). neurological functions. Decreased brain expressions of phosphorylated PDGFR-α c-Src JNK and c-Jun; as well as reduced MMP-9 activities were found in treated animals. PDGFR-α inhibition preserved BBB integrity following experimental SAH; however the protective mechanisms… Continue reading Blood-brain barrier (BBB) disruption and consequent edema formation contributes to the