A small-molecule inducer of beta-cell expansion in human being islets represents

A small-molecule inducer of beta-cell expansion in human being islets represents a potential regeneration technique for treating type 1 diabetes. an immunosuppressant used in islet transplantation. We performed a initial display of 1280 substances after that, watching some phenotypic results on cells. This high-throughput human being islet cell tradition technique can become utilized to assess… Continue reading A small-molecule inducer of beta-cell expansion in human being islets represents

Hearts utilize fatty acids as a primary source of energy. hLPL0

Hearts utilize fatty acids as a primary source of energy. hLPL0 mice had systolic dysfunction with a reduction in fractional shortening compared with age-matched controls (Fig. 1and = 5-7. … DZNep Lipid analysis. DGAT1 and -2 were reduced by the MHC-GLUT1 transgene; this would suggest that these hearts have reduced TG synthesis from FFA. However… Continue reading Hearts utilize fatty acids as a primary source of energy. hLPL0