Spontaneous regression of neuroblastoma (NB) resembles the developmentally regulated programmed cell

Spontaneous regression of neuroblastoma (NB) resembles the developmentally regulated programmed cell death (PCD) of sympathetic neurons. with E2F1 to selectively transactivate the proapoptotic target gene. The cleavage of UNC5D and its induction of apoptosis were strongly inhibited by addition of netrin-1. mice consistently exhibited a significant increase in dorsal root ganglia neurons and resistance to… Continue reading Spontaneous regression of neuroblastoma (NB) resembles the developmentally regulated programmed cell