Supplementary MaterialsSupplementary information 41598_2018_23894_MOESM1_ESM. the retina. Consistently, PERG amplitudes were significantly impaired in the eyes with targeted ablation of the Panx1 gene in RGCs. Under ocular hypertension and ischemic conditions, however, high Panx1 activity permeated cell membranes and facilitated the selective loss of RGCs or stably transfected Neuro2A cells. Our results show that high expression… Continue reading Supplementary MaterialsSupplementary information 41598_2018_23894_MOESM1_ESM. the retina. Consistently, PERG amplitudes were significantly