Background Proliferation of the vasa vasorum has been implicated in the pathogenesis of atherosclerosis, and the vasa vasorum is closely associated with resident stem cells within the vasculature. CRP-activated phosphorylation of ERK and Akt can suppress CRP-stimulated HIF-1 activation and VEGF-A manifestation. CRP can also stimulate proteolytic activity of matrix metalloproteinase-2 in ADSCs. Furthermore, CRP… Continue reading Background Proliferation of the vasa vasorum has been implicated in the