Background High-grade serous ovarian malignancies are a specific histological subtype of ovarian tumor often characterised with a dysfunctional BRCA/Fanconi anaemia (BRCA/FA) pathway, which is crucial towards the homologous recombination DNA restoration equipment. the ovarian tumor samples investigated. Summary Epigenetic silencing by DNA methylation of isn’t a common event in high-grade serous ovarian malignancies. and genes… Continue reading Background High-grade serous ovarian malignancies are a specific histological subtype of