The present work was designed to compare two mechanisms of cellular recognition based on Ab specificity: firstly, when the anti-HER2 mAb trastuzumab bridges target cells and cytotoxic lymphocytes armed with a Fc receptor (ADCC) and, secondly, when HER2 positive target cells are directly recognized by cytotoxic lymphocytes armed with a chimeric antigen receptor (CAR). ABR… Continue reading The present work was designed to compare two mechanisms of cellular
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Supplementary MaterialsSupplementary data 41598_2017_9506_MOESM1_ESM. cone cells. Mechanistically, in adult mice led
Supplementary MaterialsSupplementary data 41598_2017_9506_MOESM1_ESM. cone cells. Mechanistically, in adult mice led to a reduced scotopic photoresponse, mislocalization of ATP8A2 to the inner segment and cell body, and increased apoptosis in the retina. Our data demonstrated novel essential roles of in the retina. Introduction Phospholipids are asymmetrically distributed between the outer and inner leaflets of the… Continue reading Supplementary MaterialsSupplementary data 41598_2017_9506_MOESM1_ESM. cone cells. Mechanistically, in adult mice led