History Phosphatidylinositol-3 4 5 (PIP3) a well-known lipid second messenger takes on a key function in insulin signaling and blood sugar homeostasis. in adhesion and monocytes of monocytes to HUVEC. Exogenous PIP3 supplementation restored the intracellular PIP3 concentrations downregulated the appearance of adhesion substances and decreased the adhesion of monocytes to HUVEC treated with HG.… Continue reading History Phosphatidylinositol-3 4 5 (PIP3) a well-known lipid second messenger takes