Peptidyl-prolyl isomerization is an important post-translational modification of protein because proline is the only amino acid that can stably exist as and conformation in protein backbones. conformations, and (Figure 1). This modification causes no noticeable change in the molecular weight from the peptide or protein; hence, the shortcoming to identify this noticeable change by mass… Continue reading Peptidyl-prolyl isomerization is an important post-translational modification of protein because proline is the only amino acid that can stably exist as and conformation in protein backbones