Global efforts to avoid anthropogenic conversion of natural habitat rely heavily within the establishment of shielded areas. the influence of auto-correlation and leakage effect. Using a sample design that is not based on ways to control these biases may result in outcomes that underestimate or overestimate the effectiveness of those units. MLN4924 The matching method accounted for a bias reduction in 94C99% of the estimation of the average effect of protected areas on anthropogenic conversion and allowed us to obtain results with a reduced influence of the auto-correlation and leakage effects. Most protected areas had a positive influence on the maintenance of natural habitats, although wide variation in this effectiveness was dependent on the type, restriction, governmental sphere, size and age group of the unit. Introduction The degradation of natural habitats in the tropical zone holds an important place on political agendas, both nationally and globally. For the purpose of containing threats to natural habitat areas, some environmental plan instruments, such as for example MLN4924 environmental licensing and qualification, payment for ecosystem solutions , industrial and fiscal plans , and specifically, the establishment of shielded areas [3C5], have already been useful for biodiversity conservation. Although treated as an individual technique generally, shielded areas have already been founded for different reasons, that have been described in the Convention of Biological Variety (CBD)  aswell as by nationwide policy instruments. Mostly, the goal of these shielded areas are to safeguard ecosystems and almost all their constituent varieties, protect ecosystem solutions, protect populations of particular threatened varieties, and protect traditional ethnicities [1 actually,7,8]. Provided all of the goals of the shielded areas, research on the potency of those areas and their reasons experienced different seeks and topics of evaluation (e.g., performance on improving recreation area management, performance on shielded area system style, and performance on conservation of particular varieties IL23P19 populations). The most frequent research to day are analysis from the impact of shielded areas for the preservation of organic habitats [9,10]. With this framework, the performance may be regarded as a way of measuring the impact of shielded areas (territories with unique regulation useful and gain access to) on avoidance from the anthropogenic transformation from the organic habitat. This feature of shielded areas can vary greatly relating to local and regional variations, methods used for evaluation [9,10], or even different restriction categories, which may vary from most restrictive to the least restrictive [11C14]. As a result, some studies point out the existence of units or categories of units, of which the effects are not different from those observed for non-protected regions [15C16]. Some studies even describe negative effects of certain protected areas with regard to habitat preservation [17C18]. Naughton-Treves et al. (2005) , Nagendra (2008) , and Geldmann et al. (2013)  conducted revisions of the studies on these protected areas and noticed that the studies unequally encompass different geographic or biogeographic regions, including unequal focus on different types of habitat. Of the 141 datasets described in the previous studies, a total of 132 were forest environments, while only three were savanna or shrubs/grassland habitats. Most of these types of studies performed in Brazil referenced the Amazon biome, while a few evaluated the Cerrado Biome . The little attention given to non-forest environments, such as the Cerrado woodland savanna, is not consistent with the biological importance and the anthropogenic pressure on these areas. The Cerrado makes up about MLN4924 about 4% from the worlds biodiversity (S1 Desk). The great quantity of.