6 g53 wild-type cancers cell lines from infrequently g53-mutated organizations (neuroblastoma, rhabdomyosarcoma, and most cancers) were continuously exposed to increasing concentrations of the murine increase minute 2 inhibitor nutlin-3, resulting in the introduction of nutlin-3-resistant, g53-mutated sublines displaying a multi-drug level of resistance phenotype. U2Operating-system osteosarcoma cells and HCT116 digestive tract cancer tumor cells lead… Continue reading 6 g53 wild-type cancers cell lines from infrequently g53-mutated organizations (neuroblastoma,