Celastrol a tripterine produced from the traditional Chinese language medicine place Hook F. by inducing ROS and activating Akt/p70S6K signaling to market HIF-1α translation. Furthermore we discovered that the activation of Akt by Celastrol was transient. With an increase of exposure period inhibition of Hsp90 chaperone function by Celastrol resulted in the next depletion from… Continue reading Celastrol a tripterine produced from the traditional Chinese language medicine place