Background Carbonic anhydrase (CA) IX is normally a surface-expressed protein that’s upregulated from the hypoxia inducible factor (HIF) and represents a prototypic tumor-associated antigen that’s overexpressed about renal cell carcinoma (RCC). research demonstrate the capability of human being anti-CAIX mAbs that inhibit CA enzymatic activity to bring about immune-mediated eliminating of RCC, including character killer… Continue reading Background Carbonic anhydrase (CA) IX is normally a surface-expressed protein that’s