Background Cathepsin K, a cysteine protease predominantly expressed in osteoclasts, is a significant drug focus on for the treating osteoporosis. Lung homogenates of wild-type and cathepsin K-deficient mice had been used to judge their material of collagen, glycosaminoglycans, and TGF-1. The convenience of TGF-1 to cathepsin K-mediated degradation was identified em in vitro PU-H71 /em… Continue reading Background Cathepsin K, a cysteine protease predominantly expressed in osteoclasts, is