Immunization with high-dose warmth shock protein gp96, an endoplasmic reticulum counterpart

Immunization with high-dose warmth shock protein gp96, an endoplasmic reticulum counterpart of the Hsp90 family, significantly enhances regulatory T cell (Treg) frequency and suppressive function. of CD4+ T cells that highly express IL-2R chain RGS3 (CD25), and their differentiation and function are controlled by the forkhead/winged helix transcription factor (Foxp3) [1]. The activation and suppressive… Continue reading Immunization with high-dose warmth shock protein gp96, an endoplasmic reticulum counterpart