Supplementary MaterialsData_Sheet_1. the corresponding strain was unable to form complex colonies. In gene restored biofilm formation even at high intracellular c-di-AMP concentrations suggesting that the second messenger acts upstream of SinR in the transmission transduction pathway. As c-di-AMP accumulation did not impact the intracellular levels of SinR, we conclude that this nucleotide affects the activity… Continue reading Supplementary MaterialsData_Sheet_1. the corresponding strain was unable to form complex colonies.