Supplementary MaterialsSupplementary Information 41598_2019_41395_MOESM1_ESM. and nuclear localization, associated with induction of EGFR-regulated genes and related tumorigenic results. Each of these results could be reversed by overexpression of DUOX1 or enhanced by shRNA-dependent DUOX1 silencing. EGF-induced nuclear EGFR localization in DUOX1-deficient lung malignancy cells was associated with modified dynamics of cysteine oxidation of EGFR, and an… Continue reading Supplementary MaterialsSupplementary Information 41598_2019_41395_MOESM1_ESM. and nuclear localization, associated with induction of