Nucleotide-binding and oligomerization domain NOD-like receptors (NLRs) are highly conserved cytosolic pattern recognition receptors that perform essential functions in surveying the intracellular environment for the presence of infection, noxious substances, and metabolic perturbations. (GWASs) have identified a number of risk alleles encompassing NLR genes in a host of diseases including allergic rhinitis, multiple sclerosis, inflammatory… Continue reading Nucleotide-binding and oligomerization domain NOD-like receptors (NLRs) are highly conserved cytosolic