Although picornavirus RNA genomes contain a 3′-terminal poly(A) tract that is critical for their replication the impact of encephalomyocarditis virus (EMCV) infection within the host poly(A)-binding protein (PABP) remains unfamiliar. PABP in the absence of any virus-encoded or eukaryotic cellular cofactors. N-terminal sequencing of the producing C-terminal PABP fragment recognized a 3Cpro cleavage site on… Continue reading Although picornavirus RNA genomes contain a 3′-terminal poly(A) tract that is