We have previously observed that Wnt signaling activates a fibrogenic system in adult muscle mass stem cells called satellite cells during aging. satellite cells in an autocrine or paracrine fashion. AR-42 (HDAC-42) Indeed pharmacological inhibition of the TGFb pathway in vivo reduced the fibrogenic characteristics of satellite cells. These studies shed fresh light within the… Continue reading We have previously observed that Wnt signaling activates a fibrogenic system