Immediate analysis of the HLA-presented peptidome identifies a distinctive antigenic signature in MM. focus on antigens uncovered peptide-specific, preexisting AMD 070 Compact disc8+ T-cell replies in myeloma sufferers solely, which is certainly a sign of pathophysiological relevance. Furthermore, in vitro priming trials uncovered that peptide-specific T-cell replies can end up being activated in response-naive myeloma… Continue reading Immediate analysis of the HLA-presented peptidome identifies a distinctive antigenic signature