Mixed-lineage leukemia (proto-oncogene, which is an important regulator of hematopoietic cell

Mixed-lineage leukemia (proto-oncogene, which is an important regulator of hematopoietic cell development, has a role in leukemogenesis driven by the MLL-ENL fusion protein, but exactly how is ambiguous. ability to direct epigenetic marks, along with its participation in an autoregulatory opinions loop with genes known to transform hematopoietic cells, lends mechanistic and translationally relevant insight… Continue reading Mixed-lineage leukemia (proto-oncogene, which is an important regulator of hematopoietic cell

WUSCHEL (WUS) is vital for preventing stem cell differentiation in gain-of-function

WUSCHEL (WUS) is vital for preventing stem cell differentiation in gain-of-function mutant stem ectopic bouquets (sef) displayed elongated hypocotyls whereas the loss-of-function mutant had shortened hypocotyls. of knockdown and plant life lines supported the idea that mediates the consequences of on hypocotyl length. Jointly our data claim that ectopic appearance of in hypocotyl handles cell… Continue reading WUSCHEL (WUS) is vital for preventing stem cell differentiation in gain-of-function