We develop a multispecies continuum model to simulate the spatiotemporal dynamics of cell lineages in solid tumors. such as Dkk and SFRPs). We find that the progression of the tumors and their response to treatment is controlled by the spatiotemporal dynamics of the signaling processes. The model predicts the development of spatiotemporal heterogeneous distributions of… Continue reading We develop a multispecies continuum model to simulate the spatiotemporal dynamics